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Best CT of the mandible diagnosticians: TOP 111 doctors

author
Content meets the Bookimed Editorial Policy and is medically reviewed by
Fahad Mawlood - General practitioner. Winner of 4 scientific awards. Served in Western Asia. Former Team Leader of a medical team supporting Arabic-speaking patients. Now responsible for data processing and medical content accuracy.
Susana Akdash
Susana Akdash
Dentist
16 years of experience
4.7
113 reviews
Turkey, İzmir
WestDent Clinic

Susana Akdash

Dentist
16 years of experience

Dr. Susana Akdash is a skilled dentist who graduated from Ege University in Turkey. She focuses on implantology and dental aesthetics. Her graduation thesis was on "Implant Prosthesis and Aesthetics." She has advanced training in dental implant treatments, including All-on-4, All-on-6, and All-on-2 systems. Dr. Akdash also specializes in smile design, laminate veneers, zirconia crowns, and oral surgery.

She has attended many international seminars and congresses to improve her skills. These include the IHDE Implants Immediate Loading Course, IVOCLAR VIVADENT Smile Design Course, and several TDB and TDA congresses. Dr. Akdash uses the latest technology in her work and is dedicated to providing high-quality care in implantology and cosmetic dentistry.

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All-on-4 Dental Implants
Dental Crown Installation
Dental Crown Installation
All-on-6 Dental Implants
Zirconia crown installation
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Before and After Pictures
All-on-4 Dental Implants
Dental Crown Installation
Dental Crown Installation
All-on-6 Dental Implants
Zirconia crown installation
Dental Crown Installation
Hollywood Smile
All-on-4 Dental Implants
All-on-4 Dental Implants
Veneers
All-on-6 Dental Implants
Dental Crown Installation
Dental Crown Installation
Dental Crown Installation
All-on-6 Dental Implants
All-on-4 Dental Implants
All-on-6 Dental Implants
Dental Crown Installation
All-on-6 Dental Implants
Dental bridge installation
Porcelain Veneer
Hollywood Smile
All-on-6 Dental Implants
All-on-6 Dental Implants
Porcelain Veneer
Dental Crown Installation
Dental Crown Installation
All-on-4 Dental Implants
Dental Crown Installation
Zirconia crown installation
All-on-6 Dental Implants
Dental bridge installation
Dental bridge installation
Dental Crown Installation
Porcelain Veneer
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4.7
113 reviews
Doctor's visit price on request
Denture $500 - $700
Sinus-lifting $880 - $1090
Tooth Whitening $332.11 - $336.75
More treatments
Info
Yavuz Selim Yildirim
Yavuz Selim Yildirim
ENT doctor
18 years of experience
4.4
168 reviews
Turkey, Istanbul
Hisar Hospital Intercontinental

Yavuz Selim Yildirim

ENT doctor
18 years of experience

Dr. has a Master's Degree in Hospital and Health Institution Management and has worked in many institutions, such as the Ministry of Health Haseki Training and Research Hospital and Bezmialem University. He has attended many international conferences and won awards, and has research papers published. His fields of expertise include Nose Aesthetics, Cochlear Implant, Hearing Losses, Ear Infections, Balance Disorders, Nasal Allergies, Nasal Polyposis, Cancer Surgery, Facial Plastic Surgery, Voice Disorders, Thyroid Nodules, Sinusitis, Endoscopic Sinus Surgery, Tonsil and Adenoid Diseases and Snoring, Sleep Apnea Surgery. He has had international experiences in the US at Johns Hopkins University, Harvard University, Harvard Medical School, Boston Children's Hospital, Tufts University, and Cleveland Clinic.

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Revision rhinoplasty
Rhinoplasty (nose job)
Rhinoplasty (nose job)
Rhinoplasty (nose job)
Rhinoplasty (nose job)
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Before and After Pictures
Revision rhinoplasty
Rhinoplasty (nose job)
Rhinoplasty (nose job)
Rhinoplasty (nose job)
Rhinoplasty (nose job)
Rhinoplasty (nose job)
Rhinoplasty (nose job)
Rhinoplasty (nose job)
Rhinoplasty (nose job)
Rhinoplasty (nose job)
Ear Reconstruction
Rhinoplasty (nose job)
Otoplasty (ear surgery)
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4.4
168 reviews
Doctor's visit price on request
Stapedectomy $4000
Cochlear implant placement $18450 - $21890
Nasal polyp surgery $2500 - $4000
More treatments
Info
Tayfun Apuhan
Tayfun Apuhan
ENT doctor
27 years of experience
4.4
168 reviews
Turkey, Istanbul
Hisar Hospital Intercontinental

Tayfun Apuhan

ENT doctor
27 years of experience

Prof. Dr. Tayfun Apuhan is a specialist in ENT and Head & Neck Surgery. He is known for his skill in treating ear infections, repairing the tympanic membrane, and performing rhinoplasty and septorhinoplasty. He also has experience in adenoidectomy, tonsillectomy, sleep apnea surgery, vocal cord microsurgery, and head and neck tumor surgery. Dr. Apuhan founded the ENT and Head & Neck Surgery Department at Özel A Plus Hisar Intercontinental Hospital.

Dr. Apuhan earned his medical degree from İnönü University. He completed further training at Abant Izzet Baysal University, University Medical Center Hamburg-Eppendorf, Gazi University, and The Ohio State University Comprehensive Cancer Center. He has published over 200 scientific articles. He has also served as a session chair and editor at international conferences and journals. Dr. Apuhan currently leads the audiometry program at Doğuş University.

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Rhinoplasty (nose job)
Rhinoplasty (nose job)
Rhinoplasty (nose job)
Rhinoplasty (nose job)
Rhinoplasty (nose job)
See portfolio
Before and After Pictures
Rhinoplasty (nose job)
Rhinoplasty (nose job)
Rhinoplasty (nose job)
Rhinoplasty (nose job)
Rhinoplasty (nose job)
Rhinoplasty (nose job)
Rhinoplasty (nose job)
Rhinoplasty (nose job)
Rhinoplasty (nose job)
Rhinoplasty (nose job)
Rhinoplasty (nose job)
Rhinoplasty (nose job)
Rhinoplasty (nose job)
Rhinoplasty (nose job)
See portfolio
4.4
168 reviews
Doctor's visit price on request
Stapedectomy $4000
Cochlear implant placement $18450 - $21890
Nasal polyp surgery $2500 - $4000
More treatments
Info
Selman Sarica
Selman Sarica
ENT doctor
19 years of experience
4.4
168 reviews
Turkey, Istanbul
Hisar Hospital Intercontinental

Selman Sarica

ENT doctor
19 years of experience

Assoc. Prof. Selman Sarica, M.D., is a board-certified otorhinolaryngologist. He specializes in otology, pediatric ENT, snoring surgery, head and neck tumors, laryngology, functional nasal surgery, endoscopic sinus surgery, thyroid surgery, and salivary gland surgery. He received his medical degree from Istanbul University Cerrahpaşa Faculty of Medicine. He completed his ENT residency at Kahramanmaraş Sütçü İmam University, where he now serves as an Associate Professor.

Dr. Sarica has performed hundreds of advanced ear, nose, and throat surgeries. His experience includes complex head and neck tumor resections and endoscopic procedures. He is known for his research in voice analysis and has published several peer-reviewed articles. Dr. Sarica holds national accreditation and is respected for his clinical and academic work in ENT.

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4.4
168 reviews
Doctor's visit price on request
Stapedectomy $4000
Cochlear implant placement $18450 - $21890
Nasal polyp surgery $2500 - $4000
More treatments
Info
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Suleyman Hilmi Yilmaz
Suleyman Hilmi Yilmaz
ENT doctor
19 years of experience
4.4
168 reviews
Turkey, Istanbul
Hisar Hospital Intercontinental

Suleyman Hilmi Yilmaz

ENT doctor
19 years of experience

Dr. Süleyman Hilmi Yilmaz, M.D., is an Assistant Professor in otorhinolaryngology. He specializes in nasal congestion, nasal deformity, polyposis, lacrimal gland obstructions, head and neck tumors, and thyroid cancer. He also performs advanced ENT surgeries, including endoscopic sinus surgery and septal correction.

He graduated from Kocaeli University Faculty of Medicine in 2006. He completed his residency at Istanbul Kartal Training and Research Hospital in 2013. Dr. Yilmaz has published many articles in both local and international journals. He is a member of the Turkish Otorhinolaryngology Head and Neck Surgery Association, the Istanbul ENT-BCC Specialists Association, and the Skull Base Association.

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Rhinoplasty (nose job)
Rhinoplasty (nose job)
Rhinoplasty (nose job)
Rhinoplasty (nose job)
Otoplasty (ear surgery)
Before and After Pictures
Rhinoplasty (nose job)
Rhinoplasty (nose job)
Rhinoplasty (nose job)
Rhinoplasty (nose job)
Otoplasty (ear surgery)
See portfolio
4.4
168 reviews
Doctor's visit price on request
Stapedectomy $4000
Cochlear implant placement $18450 - $21890
Nasal polyp surgery $2500 - $4000
More treatments
Info
Suleyman Hilmi Aksoy
Suleyman Hilmi Aksoy
Radiologist
23 years of experience
4.4
168 reviews
Turkey, Istanbul
Hisar Hospital Intercontinental

Suleyman Hilmi Aksoy

Radiologist
23 years of experience

Dr. Suleyman Hilmi Aksoy was born in 1974. He graduated from Istanbul University Çapa School of Medicine in 1998. He completed his residency in Radiodiagnostics and Interventional Radiology at Cerrahpaşa School of Medicine in 2002.

He has given oral and written presentations at 13 local and international congresses. Dr. Aksoy specializes in Diagnostic Radiology, Teleradiology, and Interventional Radiology. He has made important contributions in these areas.

He has worked at Hisar Intercontinental Hospital, Merzifon Air Hospital, Istanbul Emar Center, and Haseki Training and Research Hospital. Dr. Aksoy is dedicated to improving radiological practices.

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4.4
168 reviews
Doctor's visit price on request
Stapedectomy $4000
Cochlear implant placement $18450 - $21890
Nasal polyp surgery $2500 - $4000
More treatments
Info

Find out about the best doctors here

20 top ranked CT of the mandible doctors in the world are represented on this page. The list includes only verified specialists known for their experience and high success rates.

The ranking is composed according to the Bookimed patient reviews and considers the rating of hospitals where doctors practice.

Top 5 CT of the mandible doctors on Bookimed.com:

How to choose the best CT of the mandible doctors in the world?

The specialist’s CV contains details about the doctor’s expertise and work experience, education, scientific research, and languages spoken. Compare information on several specialists, read carefully about their experience, success rates, and methods they apply. Make sure the chosen doctor has relevant experience in the treatment of a medical issue you are looking for. Read reviews of patients who had a consultation with the chosen specialist.

Famous CT of the mandible doctors have vast experience, continue education constantly, participate in professional associations and have positive feedback from patients treated.

What is the cost of a doctor's consultation?

The price for the consultation on CT of the mandible varies between experts and depends on certain factors, such as:

  • the country of practicing
  • the clinical experience and reputation
  • the medical degree and educational background
  • the doctor’s workload
  • medical developments, proprietary techniques used, and awards, if any.

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Where you go for medical treatment

Seniz Ustundag
Seniz Ustundag
Orthodontist
22 years of experience
4.4
168 reviews
Turkey, Istanbul
Hisar Hospital Intercontinental

Seniz Ustundag

Orthodontist
22 years of experience

Dr. Şeniz Üstündağ completed her dental education at Marmara University Faculty of Dentistry and was later accepted into the English doctoral program at the same faculty in 2002. She earned her doctorate in 2007 with her thesis titled “Computerized axiographic evaluation of centric occlusion-maximum intercuspation positions and condylar movements before and after relaxation splint therapy in patients with temporomandibular disorders.” Her specialization was certified in 2011. During this period, she participated in numerous national and international congresses and completed many treatments related to fixed treatments, lingual therapy, orthognathic surgery preparation, Invisalign treatments, myobrace treatments, Roth techniques, anchorage systems with mini screws, cleft lip and palate, and management of impacted teeth.

MEDICAL INTEREST AREAS

– Fixed Orthodontic Treatment

– Preventive Orthodontic Treatment

– Functional Treatments

– Treatment with Clear Aligners (Invisalign first/Teen/MA)

– Management of Impacted Teeth

– Anchorage with Mini Screws

– Preparation for Orthognathic Surgery

EDUCATION

Undergraduate: Marmara University Faculty of Dentistry

Doctorate/Specialization: Marmara University Faculty of Dentistry

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4.4
168 reviews
Doctor's visit price on request
Stapedectomy $4000
Cochlear implant placement $18450 - $21890
Nasal polyp surgery $2500 - $4000
More treatments
Info
Zuhal Tanzer
Zuhal Tanzer
Endocrinologist
36 years of experience
4.7
106 reviews
Turkey, Istanbul
Lokman Hekim Istanbul Hospital

Zuhal Tanzer

Endocrinologist
36 years of experience

Dr. Zuhal Tanzer is a specialist in Internal Diseases. She is known for her skill in diagnosing and treating complex medical conditions. Dr. Tanzer has a strong record of patient satisfaction and successful treatments. She is accredited by top medical institutions. She also takes part in ongoing medical education. Dr. Tanzer uses evidence-based methods and is dedicated to improving standards in internal medicine.

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4.7
106 reviews
Doctor's visit price on request
Dental Implant $2352 - $2571
Septoplasty (Deviated Septum Surgery) $2500 - $3000
Cochlear implant placement $19145 - $21880
More treatments
Info
Jeongwon Youn
Jeongwon Youn
Dentist
18 years of experience
Republic of Korea, Seoul
Yonsei JW Dental Clinic

Jeongwon Youn

Dentist
18 years of experience

Jeongwon Youn, Chief Doctor

D.D.S, PhD in Orthodontics
Adjunct Professor at Yonsei Univ.

Yonsei University, PhD in Orthodontics
Adjunct Professor at Yonsei University

Yonsei University College of Dentistry, D.D.S / PhD
Yonsei Serverance Hospital, Internship
Yonsei Serverance Hospital, Orthodontics Resident

Member of The Korean Association of Orthodontists 
Member of The Korean Association of Lingual Orthodontists
Member of The Yonsei University Association of Orthodontists  

Invisalign Provider Osstem 
Implant Master Course

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Tooth Whitening
Braces
Tooth Whitening
Tooth Whitening
Braces
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Before and After Pictures
Tooth Whitening
Braces
Tooth Whitening
Tooth Whitening
Braces
Tooth Whitening
Braces
See portfolio
Doctor's visit price on request
Clear braces installation $1500 - $6000
No prep veneers $700 - $1100
Laser teeth whitening $120 - $370
More treatments
Info
Tommaso Grandi
Tommaso Grandi
Dentist
21 years of experience
Italy, Modena
Tommaso Grandi Dental Clinic

Tommaso Grandi

Dentist
21 years of experience

Dr. Tommaso Grandi graduated with honors in Dentistry and Dental Prosthetics from the University of Modena and Reggio Emilia in 2004. In 2007, he was awarded a research fellowship at the Department of Neurosciences, Head and Neck Rehabilitation at the same university.

From 2008 to 2013, he served as Adjunct Professor of Periodontology at the University of Modena and Reggio Emilia.

In 2013, he founded the Tommaso Grandi Dental Clinic, a center dedicated to clinical care, scientific research, and professional training in the field of dental implantology.

Dr. Grandi has collaborated with international colleagues on research related to immediate loading protocols in implant dentistry. He is the primary author of several peer-reviewed scientific publications in internationally recognized implantology journals.

Thanks to his ongoing contribution to research, he was invited to join the Editorial Board of the European Journal of Oral Implantology, one of the most prestigious journals in the field. He is also a frequent speaker at courses and conferences in Italy and abroad.

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Dental Implant
Full-Arch Implant-Fixed Complete Dentures in Monolithic Zirconia (6 titanium implants)
Full-Arch Implant-Fixed Complete Dentures in Monolithic Zirconia (6 titanium implants)
All-on-4 Dental Implants
All-on-4 Dental Implants
See portfolio
Before and After Pictures
Dental Implant
Full-Arch Implant-Fixed Complete Dentures in Monolithic Zirconia (6 titanium implants)
Full-Arch Implant-Fixed Complete Dentures in Monolithic Zirconia (6 titanium implants)
All-on-4 Dental Implants
All-on-4 Dental Implants
Full-Arch Implant-Fixed Complete Dentures in Monolithic Zirconia (6 titanium implants)
Full-Arch Implant-Fixed Complete Dentures in Monolithic Zirconia (6 titanium implants)
Dental Implant
Full-Arch Implant-Fixed Complete Dentures in Monolithic Zirconia (6 titanium implants)
See portfolio
Doctor's visit price on request
All-on-6 Dental Implants $9289.76
Root canal treatment $220.63 - $348.37
Zirconia All-on-4 dental implants
More treatments
Info
Ismail Eser Bolat
Ismail Eser Bolat
Oral and maxillofacial surgeon
12 years of experience
5.0
5 reviews
Turkey, Istanbul
Hospitadent Dental Group - İstanbul Mecidiyeköy Clinic

Ismail Eser Bolat

Oral and maxillofacial surgeon
12 years of experience

Oguz Akca - dentist, 4 years of practical experience.

Education

Graduated from the Faculty of Dentistry at Marmara University.

Internships and Seminars

  • Advanced training at the University of California, Department of Oral and Maxillofacial Surgery, 2013.
  • 2nd Spring Dental Symposium, 2013.
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All-on-4 Dental Implants
All-on-4 Dental Implants
Dental Implant
Dental Implant
Dental Implant
See portfolio
Before and After Pictures
All-on-4 Dental Implants
All-on-4 Dental Implants
Dental Implant
Dental Implant
Dental Implant
All-on-6 Dental Implants
Dental Implant
All-on-6 Dental Implants
All-on-4 Dental Implants
Dental Implant
All-on-6 Dental Implants
See portfolio
5.0
5 reviews
Info
Volkert Boudewijn Wreesmann
Volkert Boudewijn Wreesmann
ENT doctor
14 years of experience
Spain, Barcelona
ANDSURGEONS

Volkert Boudewijn Wreesmann

ENT doctor
14 years of experience

CURRICULUM VITAE

VOLKERT B. WREESMANN MD PhD

Consultant Otolaryngologist

Oncologic Head and Neck Surgeon

Thyroid and Parathyroid Surgeon

Facial Plastic Surgeon

 

Principal Positions

  • Centro Medico Teknon, Barcelona, Spain

Chairman, Department of Otolaryngology-Head and Neck Surgery

July 1st 2024 – present

 

  • Juaneda, Ciutadella Menorca, Spain

Consultant Otolaryngologist-Head and Neck Surgeon

January 2025 – present

 

  • Avantmedic, Lleida, Spain

Consultant Otolaryngologist-Head and Neck Surgeon

July 1st 2024 – present

 

  • Clinica Omega Zeta, Andorra

Consultant Otolaryngologist-Head and Neck Surgeon

March 1st 2022 – present

 

  • University Hospitals Dorset NHS Foundation Trust

Consultant Otolaryngologist-Head and Neck Surgeon

August 1st 2021 – October 1st 2023

 

  • Oxford University Hospitals NHS Foundation Trust

Honorary Consultant Otolaryngologist-Head and Neck Surgeon

May 1st 2021 – April 30th 2024

 

  • Portsmouth Hospitals University NHS Trust, Portsmouth, UK

Consultant Otolaryngologist-Head and Neck Surgeon

July 18th 2016 – April 30th 2021

 

  • Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK

Consultant Otolaryngologist-Head and Neck Surgeon

November 7th 2015 – May 31st 2016

 

  • Heart of England NHS Trust, Birmingham, UK

Consultant Otolaryngologist-Head and Neck Surgeon

March 1st 2015 – October 31st 2015

 

  • University Medical Center Utrecht, Netherlands

Consultant Otolaryngologist-Head and Neck Surgeon

November 1st 2013 – June 1st 2014

 

Memberships

  • American Head and Neck Society – Member

Netherlands Academy of Otolaryngology - Member

 

Professional Licences

  • United Kingdom

GMC Certification

Fully Registered Medical Practitioner with Specialist Registration with a License to Practice

Registered: 02/02/2015

GMC # 7499626

 

  • United States of America

New York State Department of Health

New York State Education Department

Registered: July 2011

License# P80949

Physician

 

  • Netherlands

Dutch Ministry of Health (BIG Registration)

BIG Registered: 22-06-2005

BIG #19063373601

Physician

 

Dutch Specialist Board (RGS)

RGS registered: 01-02-2011

RGS #1911979

Otolaryngology-Head and Neck Surgeon

 

  • Spain

Collegi de Metges de Barcelona

COMB: 63638

 

  • Andorra

Collegi de Metges d’Andorra

RPS: 03098

COMA: 876

Education

  • Memorial Sloan-Kettering Cancer Center

Surgical Fellowship, Head and Neck Surgery

New York, New York, USA

August 1st 2011 - July 31st 2013

600 bed dedicated cancer center

Performed 1200 major oncologic head and neck resections in 2 years

 

  • United States of America ECFMG Certification

United States Medical Licensing Examination (USMLE)

Certification: June 22nd, 2010

Scores: 

   Step I: 244/99 

   Step IIa-Clinical knowledge: 227/94

   Step IIb-Clinical Skills: PASSED

   Step III: 206/85

 

  • Netherlands Cancer Institute

Surgical Fellowship, Head and Neck Surgery

Amsterdam, The Netherlands

February 1st 2011 - July 31st 2011

Specialized Head and Neck Cancer Surgery Department

200 bed hospital

 

  • Amsterdam University Medical Center/Netherlands Cancer Institute

Residency Training, Otolaryngology-Head and Neck Surgery

Amsterdam, the Netherlands

February 1st 2006 – January 31st 2011

 

  • University of Amsterdam School of Medicine

Medical Doctor (MD)

Amsterdam, the Netherlands

December 2002 - January 28th 2005

 

  • University of Amsterdam

Doctor of Philosophy (PhD), Molecular Biology

Amsterdam, the Netherlands

Thesis title: Molecular-cytogenetic characterization of head and neck cancer

December 2nd, 2004

 

  • Erasmus University School of Medicine

Doctoral Degree in Medicine

Rotterdam, the Netherlands

September 1994 - November 17th, 1998

 

Research Training

  • Memorial Sloan-Kettering Cancer Center

Laboratory of Epithelial Cancer Biology, Head and Neck Service, Department of Surgery, New York, New York, USA

Research Fellowship in Molecular Oncology

Supervisors: Dr. Bhuvanesh Singh MD, PhD and Dr. Jatin P. Shah, MD, FACS

March 1st 1999 - September 30st 2002

 

  • University of California San Francisco (UCSF)

Department of Otolaryngology-Head and Neck Surgery, San Francisco, California, USA

Post-doctoral Research Fellowship in Head and Neck Oncology

Supervisors: Dr. Steven Wang MD And Prof David Eisele MD

February 2005 - January 2006

 

Academic Activities

University of Amsterdam

 

Doctorate Examination Committee member

  • September 17th, 2013 - PhD Candidate: Dr. I.J. Nixon (United Kingdom)
  • October 17th 2014 - PhD Candidate: Dr. J. Pramana (Netherlands)
  • November 17th 2015 - PhD candidate: Dr. H. van Monsjou (Netherlands)
  • December 11th 2018 - PhD Candidate: Dr. Tihana Ibrahimpasic (United States)
  • January 18th, 2021 - PhD Candidate: Dr. Laura Wang (Australia)
  • June 2nd, 2021 - PhD Candidate: Dr. Caroline Verhagen (Netherlands)

 

Conference Faculty

  • Advanced Laryngopharyngeal Cancer: Functional Preservation and Rehabilitation, Portsmouth, June 25th - 26th, 2020 (postponed due to COVID) - Chairman
  • Functional Preservation and Rehabilitation after Treatment for Advanced Laryngeal Cancer, Portsmouth, March 14th - 15th, 2019 - Chairman
  • Portsmouth Parathyroid Conference, Portsmouth, December 14th 2018 – Chairman

 

Editorial Roles

  • European Journal of Surgical Oncology

Associate Editor

January 1st 2023 – present

 

  • European Journal of Surgical Oncology

Guest Editor

March issue 2018, Volume 44, Issue 3, p275-378 - Special issue on thyroid cancer management

 

  • Journal of Oral Pathology and Medicine

Guest Editor

November issue 2021, Volume 51, Issue 10 - Special issue on vascular malformations and tumors of the head and neck

 

  • Scientific Journal Reviewer

Oral Oncology, European Journal of Surgical Oncology, Journal of Surgical Oncology, Head and Neck, International Journal of Cancer

 

  • Scientific Project and Grant Reviewer

Netherlands: Dutch Cancer Society

France: Institute National du Cancer

 

Awards

  • New York Head and Neck Society

Annual Meeting, New York, NY, March 2002

Title of study presented: “MUC1 is a target if 1q amplification and pertains a grave clinical prognosis in papillary thyroid cancer”

 

Invited Lectures

  • European Society of Surgical Oncology meeting, Krakow, 2016
  • Barcelona Society of Neurosurgery, Annual Meeting, Baqueira, Spain, February, 2017
  • University of Edinburgh, Department of Otolaryngology Academic Conference, March 17th 2017
  • Medilex: Performance of Medical Specialists, Zeist, Netherlands, November 9th 2017
  • Medilex: Performance of Medical Specialists, Driebergen, Netherlands, October 11th 2017
  • Wessex Head and Neck and Thyroid Network Education Day, May 3rd, 2017
  • Portsmouth Parathyroid Conference, Portsmouth, UK, December 14th 2018
  • Global Post-laryngectomy Rehabilitation Academy, Portsmouth, UK, March 14th 2019
  • Health Care Quality Conference, Beverwijk, Netherlands, March 25th, 2019

 

Published Research Reports

  • The growing precision of diagnostic pathways in thyroid nodule evaluation. 

Bekker J, Wreesmann VB. 

Eur J Surg Oncol. 2025 Jan;51(1):109374.

 

  • Special issue: Management of vascular tumors and malformations of the head and neck. 

Oomen KPQ, Brennan PA, Wreesmann VB. 

J Oral Pathol Med. 2022 Nov;51(10):829.

 

  • Angiosarcomas of the head and neck: Impact of large data analysis on clinical management.
  •  
  • Wreesmann VB, Oomen KP, Brennan PA.

J Oral Pathol Med. 2022 Nov;51(10):904-910.

 

  • Current classification of vascular anomalies of the head and neck. 

Oomen KPQ, Wreesmann VB. 

J Oral Pathol Med. 2022 Nov;51(10):830-836.

 

  • A novel classification of carotid body tumors.

Wreesmann VB, Nixon IJ. 

Eur. J. Surg. Oncol. May, 2021

 

  • Management of the contralateral central neck in differentiated thyroid cancer: A contentious issue. 

Shaha AR, Tuttle RM, Wreesmann VB. 

Eur. J. Surg. Oncol. 2021 Apr;47(4):717-719.

 

  • Improvement of oral cancer screening quality and reach: The promise of artificial intelligence.
  •  
  • Kar A, Wreesmann VB, Shwetha V, Thakur S, Rao VUS, Arakeri G, Brennan PA.

J Oral Pathol Med. 2020 Mar 11

 

  • The risk-benefit ratio of chemoradiation treatment in head and neck squamous cell carcinoma: value of extranodal spread and margin status. 

Ammar M, Wreesmann VB. 

Journal of ENT Masterclass, Yearbook 2018, Volume 11, Nr. 1, December 1st, 2018

 

  • Nasal obstruction secondary to an inverted midline supernumerary tooth. 

Jones L, Hilton JM, Heyman J, Viswanathan H, Wreesmann VB, Hayes SM. 

Ann R Coll Surg Engl. 2019 Jan;101(1)

 

  • Fanconi anemia and homologous recombination gene variants are associated with functional DNA repair defects in vitro and poor outcome in patients with advanced head and neck squamous cell carcinoma. 

Verhagen CVM, Vossen DM, Borgmann K, Hageman F, Grénman R, Verwijs-Janssen M, Mout L, Kluin RJC, Nieuwland M, Severson TM, Velds A, Kerkhoven R, O'Connor MJ, van der Heijden M, van Velthuysen ML, Verheij M, Wreesmann VB, Wessels LFA, van den Brekel MWM, Vens C. 

Oncotarget. 2018 Apr 6;9(26):18198-18213.

 

  • Complete nasal obstruction secondary to pacemaker insertion. 

Jones TL, Wreesmann VB, Nilssen E, Hilton J, Hayes SM. 

Ann R Coll Surg Engl. 2018 May;100(5)

 

  • Optimization of the risk-benefit ratio of differentiated thyroid cancer treatment. 

Nasef HO, Nixon IJ, Wreesmann VB. Eur J Surg Oncol. 

2018 Mar;44(3):276-285. Review.

 

  • The risk/benefit ratio of differentiated thyroid cancer treatment: Exploring treatment de-escalation. 

Wreesmann VB; on behalf of EJSO. 

Eur J Surg Oncol. 2018 Mar;44(3):275.

 

  • Aggressive differentiated thyroid cancer. 

Janjua N, Wreesmann VB. 

Eur J Surg Oncol. 2018 Mar;44(3):367-377. Review.

 

  • Role of extracapsular nodal spread and surgical margin status in defining high-risk head and neck squamous cell carcinoma and its treatment intensity. 

Wreesmann VB. 

International Journal of Head and Neck Surgery, April-June 2017; 8(2): 76-83.

 

  • An International Multi-Institutional Validation of Age 55 Years as a Cutoff for Risk Stratification in the AJCC/UICC Staging System for Well-Differentiated Thyroid Cancer.              

Nixon IJ, Wang LY, Migliacci JC, Eskander A, Campbell MJ, Aniss A, Morris L, Vaisman F, Corbo R, Momesso D, Vaisman M, Carvalho A, Learoyd D, Leslie WD, Nason RW, Kuk D, Wreesmann V, Morris L, Palmer FL, Ganly I, Patel SG, Singh B, Tuttle RM, Shaha AR, Gönen M, Pathak KA, Shen WT, Sywak M, Kowalski L, Freeman J, Perrier N, Shah JP. 

Thyroid. 2016 Mar;26(3):373-80.

 

  • Influence of extracapsular nodal spread extent on prognosis of oral squamous cell carcinoma. 
  •  
  • Wreesmann VB, Katabi N, Palmer FL, Montero PH, Migliacci JC, Gönen M, Carlson D, Ganly I, Shah JP, Ghossein R, Patel SG.

Head Neck. 2016 Apr;38 Suppl 1:E1192-9.

 

  • Defining a Valid Age Cutoff in Staging of Well-Differentiated Thyroid Cancer. 

Nixon IJ, Kuk D, Wreesmann V, Morris L, Palmer FL, Ganly I, Patel SG, Singh B, Tuttle RM, Shaha AR, Gönen M, Shah JP. 

Ann Surg Oncol. 2015 Jul 28.

 

  • Prognostic value of vascular invasion in well-differentiated papillary thyroid carcinoma.
  •  
  • Wreesmann VB, Nixon IJ, Rivera M, Katabi N, Palmer F, Ganly I, Shaha AR, Tuttle RM, Shah JP, Patel SG, Ghossein RA.

Thyroid. 2015 May;25(5):503-8.

 

  • Head and neck squamous cell carcinoma in young patients.

van Monsjou HS, Wreesmann VB, van den Brekel MW, Balm AJ. 

Oral Oncol. 2013 Dec;49(12):1097-102.

 

  • Oral and oropharyngeal squamous cell carcinomas in young patients: The Netherlands Cancer Institute experience. 

van Monsjou HS, M Lopez-Yurda, M. Hauptmann, Balm AJ, van den Brekel MM, Wreesmann VB. 

Head Neck. 2013 Jan;35(1):94-102.

 

  • Oropharyngeal squamous cell carcinoma: a unique disease on the rise?

van Monsjou HS, Balm AJ, van den Brekel MM, Wreesmann VB. 

Oral Oncol. 2010 Nov;46(11):780-5.

 

  • Closure of tracheoesophageal fistula with prefabricated revascularized bilaminar radial forearm free flap.

Wreesmann VB, Smeele LE, Hilgers FJ, Lohuis PJ. 

Head Neck. 2009 Jun;31(6):838-42.

 

  • Clinical impact of molecular analysis on thyroid cancer management.

Wreesmann VB, Singh B. 

Surg Oncol Clin N Am. 2008 Jan;17(1):1-35.

 

Genetic abnormalities associated with chemoradiation resistance of head and neck squamous cell carcinoma. 

van den Broek GB, Wreesmann VB, van den Brekel MW, Rasch CR, Balm AJ, Rao PH. 

Clin Cancer Res. 2007 Aug 1;13(15 Pt 1):4386-91.

 

  • Association of CD44 V3-containing isoforms with tumor cell growth, migration, matrix metalloproteinase expression, and lymph node metastasis in head and neck cancer.

Wang SJ, Wreesmann VB, Bourguignon LY. 

Head Neck. 2007 Jun;29(6):550-8.

 

  • Downregulation of Fanconi anemia genes in sporadic head and neck squamous cell carcinoma.
  •  
  • Wreesmann VB, Estilo C, Eisele DW, Singh B, Wang SJ.

ORL J Otorhinolaryngol Relat Spec. 2007;69(4):218-25. Epub 2007 Apr 4.

 

  • Patterns of expression of cell cycle/apoptosis genes along the spectrum of thyroid carcinoma progression.
  •  
  • Saltman B, Singh B, Hedvat CV, Wreesmann VB, Ghossein R.
  •  
  • Surgery. 2006 Dec;140(6):899-905; discussion 905-6.

 

  • Repetitive endoscopic sinus surgery failure: a role for radical surgery?

Videler WJ, Wreesmann VB, van der Meulen FW, Knegt PP, Fokkens WJ. 

Otolaryngol Head Neck Surg. 2006 Apr;134(4):586-91.

 

  • MUC1 plays a role in tumor maintenance in aggressive thyroid carcinomas.
  •  
  • Patel KN, Maghami E, Wreesmann VB, Shaha AR, Shah JP, Ghossein R, Singh B.
  •  
  • Surgery. 2005 Dec;138(6):994-1001; discussion 1001-2.

 

  • Chromosomal aberrations in squamous cell carcinomas of the upper aerodigestive tract: biologic insights and clinical opportunities.

Wreesmann VB, Singh B. 

J Oral Pathol Med. 2005 Sep;34(8):449-59. Review.

 

  • Molecular profiling of tumor progression in head and neck cancer.
  •  
  • Belbin TJ, Singh B, Smith RV, Socci ND, Wreesmann VB, Sanchez-Carbayo M, Masterson J, Patel S, Cordon-Cardo C, Prystowsky MB, Childs G.
  •  
  • Arch Otolaryngol Head Neck Surg. 2005 Jan;131(1):10-8.

 

  • Identification of novel prognosticators of outcome in squamous cell carcinoma of the head and neck.

Wreesmann VB, Shi W, Thaler HT, Poluri A, Kraus DH, Pfister D, Shaha AR, Shah JP, Rao PH, Singh B. 

J Clin Oncol. 2004 Oct 1;22(19):3965-72.

 

  • Follicular variant of papillary thyroid carcinoma: genome-wide appraisal of a controversial entity.

Wreesmann VB, Ghossein RA, Hezel M, Banerjee D, Shaha AR, Tuttle RM, Shah JP, Rao PH, Singh B. 

Genes Chromosomes Cancer. 2004 Aug;40(4):355-64.

 

  • Genome-wide profiling of papillary thyroid cancer identifies MUC1 as an independent prognostic marker.

Wreesmann VB, Sieczka EM, Socci ND, Hezel M, Belbin TJ, Childs G, Patel SG, Patel KN, Tallini G, Prystowsky M, Shaha AR, Kraus D, Shah JP, Rao PH, Ghossein R, Singh B. 

 

Cancer Res. 2004 Jun 1;64(11):3780-9.

 

  • Genetic abnormalities associated with nodal metastasis in head and neck cancer.

Wreesmann VB, Wang D, Goberdhan A, Prasad M, Ngai I, Schnaser EA, Sacks PG, Singh B. 

Head Neck. 2004 Jan;26(1):10-5.

 

  • Human papillomavirus DNA and p53 polymorphisms in squamous cell carcinomas from Fanconi anemia patients.
  •  
  • Kutler DI, Wreesmann VB, Goberdhan A, Ben-Porat L, Satagopan J, Ngai I, Huvos AG, Giampietro P, Levran O, Pujara K, Diotti R, Carlson D, Huryn LA, Auerbach AD, Singh B.
  •  
  • J Natl Cancer Inst. 2003 Nov 19;95(22):1718-21.

 

  • Chromosomal aberrations in patients with head and neck squamous cell carcinoma do not vary based on severity of tobacco/alcohol exposure.

Singh B, Wreesmann VB, Pfister D, Poluri A, Shaha AR, Kraus D, Shah JP, Rao PH. 

BMC Genet. 2002 Nov 14;3:22. Epub 2002 Nov 14.

 

  • Genome-wide appraisal of thyroid cancer progression.
  •  
  • Wreesmann VB, Ghossein RA, Patel SG, Harris CP, Schnaser EA, Shaha AR, Tuttle RM, Shah JP, Rao PH, Singh B.
  •  
  • Am J Pathol. 2002 Nov;161(5):1549-56.

 

  • Refractory chronic sinusitis: evaluation of symptom improvement after Denker’s procedure.
  •  
  • Wreesmann VB, Fokkens WJ, Knegt PP.
  •  
  • Otolaryngol Head Neck Surg. 2001 Nov;125(5):495-500.

 

  • Inflammatory pseudotumour (inflammatory myofibroblastic tumour) of the pancreas: a report of six cases associated with obliterative phlebitis.
  •  
  • Wreesmann V, van Eijck CH, Naus DC, van Velthuysen ML, Jeekel J, Mooi WJ.
  •  
  • Histopathology. 2001 Feb;38(2):105-10.

 

  • Screening for genetic aberrations in papillary thyroid cancer by using comparative genomic hybridization.
  •  
  • Singh B, Lim D, Cigudosa JC, Ghossein R, Shaha AR, Poluri A, Wreesmann VB, Tuttle M, Shah JP, Rao PH.
  •  
  • Surgery. 2000 Dec;128(6):888-93;discussion 893-4.

 

Abstracts (Presentations at scientific meetings):

 

  • Genome-wide screening for genetic prognostic factors in papillary thyroid carcinoma.
  •  
  • Wreesmann VB, Ghossein RA, Poluri A, Shaha AR, Tuttle RM, Shah JP Rao PH, Singh B.

Fifth International Conference on Head and Neck Cancer San Francisco, CA, July 2000.

 

  • Hierarchical Clustering (HC): a Novel Approach to Evaluating the Prognostic Value of Laboratory Parameters in Patients (Pts) Undergoing Chemoradiation Treatment (CRT) for Advanced Laryngopharyngeal Carcinoma (LPC). 

Singh B, Pfister D, Wreesmann VB, Li R, Gogineni S, Bosl G, Hoffman RH, Shah JP, Rao PH. 

37th Annual Meeting of the American Society of Clinical Oncology; New Orleans LA, May 2001.

 

  • Gain of 1q is unique to the tall cell variant of papillary thyroid cancer.

Wreesmann VB, Ghossein RA, Tuttle RM, Shaha AR, Robbins R, Shah JP, Rao PH, Singh B. 

73rd annual meeting of the American Thyroid Association, Washington D.C. November 2001.

 

  • MUC1 is a target of 1q amplification and pertains a grave clinical prognosis in papillary thyroid cancer. 

Wreesmann VB, Sieczka E, Socci ND, Hezel M, Belbin TJ, Childs G, Patel SG, Shah JP, Rao PH, Ghossein RG, Singh B. 

Annual Meeting of the New York Head and Neck Society, New York, NY, March 2002.

 

  • Genome wide screening identified gains and losses as independent prognostic variables in patients with head and neck squamous cell carcinoma (HNSCC). 

Singh B, Wreesmann VB, Thaler HT, Shi W, Shah JP, Shaha AR, Kraus DH, Boyle JO, Pfister D, Rao PH. 

38th Annual Meeting of the American Society of Clinical Oncology; Orlando, Fl May 2002.

 

  • p53 inactivation by human papillomavirus (HPV) in Fanconi anemia associated squamous cell carcinoma. 

Kutler DI, Goberdhan A, Wreesmann VB, Giampietro PF, Auerbach AD, Singh B. 

The Sixth Research Workshop on the Biology, Prevention, and Treatment of Head and Neck Cancer; Washington D.C.; October 2002.

 

  • Identification of novel prognostic factors in head and neck squamous cell carcinoma. 
  •  
  • Wreesmann VB, Shi W, Thaler HT, Shah JP, Shaha AR, Kraus DH, Boyle JO, Pfister D, Rao PH, Singh B. 

7th symposion on Research in Head and Neck Cancer; Dusseldorf, Germany, September 4-6 2003.

 

  • Molecular profiling of aggressive papillary thyroid cancer: prognostic significance of MUC1 alterations. 

Wreesmann VB, Sieczka E, Socci ND, Hezel M, Belbin TJ, Childs G, Patel SG, Patel KN, Tallini G, Prystowsky M, Shaha AR, Kraus D, Shah JP, Rao PH, Ghossein RA, Singh B. 

7th symposion on Research in Head and Neck Cancer; Dusseldorf, Germany, September 4-6 2003.

 

  • Chromosomal aberrations in Fanconi anemia-associated squamous cell carcinomas differ from sporadic squamous cell carcinomas from the general population. 

Kutler DI, Rao PH, Wreesmann VB, Goberdhan A, Ngai I, Huvos AG, Giampietro PF, Levran O, Pujara K, Diotti R, Auerbach AD, Singh B. 

15th annual Fanconi Anemia Research Fund scientific symposium, Houston TX, Oct 2003.

 

  • Molecular classification of Fanconi anemia(FA)-associated head and neck squamous cell carcinoma (HNSCC) using oligonucleotide microarrays. 

Kutler DI, Ganly I, Wreesmann VB, Goberdhan A, Ngai I, Huvos AG, Giampietro PF, Levran O, Pujara K, Diotti R, Auerbach AD, Singh B. 

15th annual Fanconi Anemia Research Fund scientific symposium, Houston TX, Oct 2003.

  •  
  • Genotyping follicular cell-derived thyroid neoplasia: a CGH study of 150 cases.

Wreesmann VB, Ghossein RA, Socci N, Shaha AR, Tuttle RM, Shah JP, Rao PH, Singh B. 

Sixth International Conference on Head and Neck Cancer, Washington DC, August 2004.

 

  • Downregulation of Fanconi anemia genes in sporadic squamous cell carcinomas of the head and neck. 

Wreesmann VB, Estilo C, Eisele DW, Singh B, Wang SJ. 

208th meeting of the Netherlands Society of Otolaryngology-Head and Neck Surgery, Utrecht, April 7th 2006.

 

  • Extracapsular nodal spread does not predict outcome in clinically node negative oral cavity squamous cell carcinoma. 

Wreesmann VB, Ghossein RA, Carlson D, Ganly I, Palmer F, Montero P, Shah JP, Patel SG. 

AHNS 2013 Annual Meeting, April 10 & 11, 2013, Orlando Florida.

 

  • Minor (<2mm) extracapsular spread is not an adverse predictor of outcome in metastatic squamous cell carcinoma of the oral cavity. 

Wreesmann VB, Ghossein RA, Carlson D, Ganly I, Palmer F, Montero P, Shah JP, Patel SG. Presented at the AHNS 2014 Annual Meeting, July 2014, New York, New York.

 

Books, Chapters:

 

  • Molecular Biology as applied to Head and Neck Oncology

Wreesmann VB, Singh B.

Stell and Maran's Textbook of Head and Neck Surgery and Oncology

Fifth Edition

Chapter, edited by John Watkinson and Ralph Gilbert

 

  • Molecular-Cytogenetic Characterization of Head and Neck Cancer: Identification of molecular prognostic factors and targets of therapy

Wreesmann VB, Singh B.

Book, Amsterdam 2004

Reviewed in: Head and Neck: Volume 29, Issue 1, pages 82–83, January 2007

 

  • Open Conservation Surgery for Laryngeal Cancer

Wreesmann VB, Ganly I

Scott-Brown's Otorhinolaryngology and Head and Neck Surgery, Eighth Edition

Chapter 27

CRC Press, Taylor-Francis Group, June 12th, 2018

 

  • Molecular Oncology

Wreesmann V.B.

Self-Assessment in Head and Neck Surgery and Oncology, First Edition

Chapter 21

Elsevier 2014

 

Research grants:

Netherlands Cancer Institute “Startgeld” Grant 2008

Project: Fanconi anemia in head and neck cancer

Principal investigators: Wreesmann VB, van den Brekel MW, Balm AJM, Vens C.

Amount granted: 300.000 euro

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